Senior Scientist, Cryo-Electron Microscope (Cryo-EM)

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Job Title: Senior Scientist, Cryo-Electron Microscope (Cryo-EM)

Company Name:	Johnson & Johnson
Location:	Spring House, PA
Position Type:	Full Time
Post Date:	04/01/2026
Expire Date:	05/08/2026
Job Categories:	Healthcare, Other, Science, Medical

Job Description

Senior Scientist, Cryo-Electron Microscope (Cryo-EM)
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at <a target="_blank" href="https://www.jnj.com.">jnj.com</a>.As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.Job Function: Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function: Biological ResearchJob Category:Scientific/TechnologyAll Job Posting Locations:Spring House, Pennsylvania, United States of AmericaJob Description:Employer: Janssen Research & Development, LLCJob Title: Senior Scientist, Cryo-Electron Microscope (Cryo-EM)Job Code: A011.6969.7Job Location: Spring House, PAJob Type: Full-TimeJob Duties: Serve as an integral member of cross-functional discovery project teams, collaborating closely with computational and medicinal chemists and biologists to drive structure-based drug design for both small and large molecule optimization. Lead end-to-end structure determination of challenging targets using single-particle Cryo-EM, including sample optimization, grid preparation, data collection, processing, and structural analysis. Partner with protein scientists, biophysicists, and experts in protein NMR and X-ray crystallography to implement an integrated structural biology strategy. Design and implement innovative approaches for the expression, purification, and characterization of membrane proteins for Cryo-EM based structure determination. Clearly communicate structural findings and insights to project teams, contributing to data-driven decision-making for structure-based drug design in a timely manner. Contribute to the scientific leadership of the group by mentoring junior scientists, participating in strategic planning, and implementing impactful new technologies and techniques. Stay at the forefront of the field by publishing high-impact research papers, attending and presenting at scientific conferences, and establishing academic collaborations with key opinion leaders.Requirements: Employer will accept a Ph.D. degree in Biochemistry, Structural Biology, Molecular Biology, Pharmacology or related field and 1 year of experience in the job offered or in a Senior Scientist, Cryo-Electron Microscope (Cryo-EM)- related occupation. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via <a href="https://www.jnj.com/contact-us/careers" target="_blank">https://www.jnj.com/contact-us/careers</a> . Internal employees contact AskGS to be directed to your accommodation resource.Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).This position is eligible to participate in the Company’s long-term incentive program.Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:<ul><li>Vacation –120 hours per calendar year</li><li>Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year</li><li>Holiday pay, including Floating Holidays –13 days per calendar year</li><li>Work, Personal and Family Time - up to 40 hours per calendar year</li><li>Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child</li><li>Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year</li><li>Caregiver Leave – 80 hours in a 52-week rolling period10 days</li><li>Volunteer Leave – 32 hours per calendar year</li><li>Military Spouse Time-Off – 80 hours per calendar year</li><li>This position is eligible for benefits to include medical, dental, vision and time off, as well as any others as provided for in the applicable Collective Bargaining Agreement.</li><li>For additional general information on Company benefits, please go to: - <a href="https://www.careers.jnj.com/employee-benefits" target="_blank">https://www.careers.jnj.com/employee-benefits</a></li></ul> Required Skills: Preferred Skills:

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